李文君

个人简介

主要研究方向为:食品安全、食品营养与多肽化员工物学。希望能有机会和大家一起享受在食品多肽领域专业技能运用和科研思维探索的乐趣,为食品领域生物活性多肽的鉴定、修饰、优化和食品安全检测提供更多思路和参考。

工作经历

教育经历

2011.09-2015.06 中山大学 化员工物学专业学习,获理学学士学位;2015.08-2020.08 北京大学 化学(化学基因组学)专业 硕博连读,获理学博士学位

研究方向

食品安全方向:食品安全检测方法的开发、食品中新型污染物污染水平分析;

食品营养方向:食品功能因子递送

多肽化员工物学方向:基于订书肽策略的新型抗菌肽分子开发


学术成果

食品安全方向

[1] Li, W., Chen, J., Linli, F., Chen, X., Huang, Y., Yang, X. Organophosphorus pesticide contaminants in fruits and vegetables: A meta-analysis. Food Chem. X, 2023, 20, 101014.

[2]  Li, W., Chen, J., Chen, X., Linli, F., Yang, X., Wang, L., Zhang K. Universal organophosphate pesticides detection by peptide based fluorescent probes. TALANTA. accepted.

食品营养方向:

[1] Li, W., Linli, F., Yang, W. Enhancing the stability of natural anthocyanins against environmental stressors through encapsulation with synthetic peptide hydrogels. Int. J. Biol. Macromol. 2023, 253, 127133.

多肽化员工物学方向:

[1] Li, W. #, Zhang, Y. #, Wang, Y. #, Ma, Y., Wang, D., Li, H., Ye, X., Yin. F. & Li, Z. “Nucleic acids induced peptide-based AIE nanoparticles for fast cell imaging. ” Chinese Chem. Lett., 2021, 32(4), 1573-1576.

[2] Li, W.#, Gao, Y.#, Zhang, J., Wang, X., Yin, F., Li, Z. & Zhang, M. “Universal DNA detection realized by peptide-based carbon nanotube biosensors.” Nanoscale Adv.20202(2), 717-723.

[3] Ma, Y.#Li, W.#, Zhou, Z., Qin, X., Wang, D., Gao, Y., Yu, Z., Yin, F. & Li, Z. “Peptide-aptamer co-assembly nanocarrier for cancer therapy.” Bioconjugate Chem.201930(3), 536-540.

[4] Wang, D., Li, W., Zhao, R., Chen, L., Liu, N., Tian, Y., Zhao, H., Xie, M., Lu, F., Fang, Q., Liang, W., Yin, F. & Li, Z. “Stabilized peptide HDAC inhibitors derived from HDAC1 substrate H3K56 for the treatment of cancer stem–like cells in vivo. ” Cancer Res., 2019, 79(8), 1769-1783.

[5] Li, W., Wang, D., Shi, X., Li, J., Ma, Y., Wang, Y., Li, T., Zhang, J., Zhao, R., Yu Z., Feng, Y. & Li, Z., “A siRNA-induced peptide co-assembly system as a peptide-based siRNA nanocarrier for cancer therapy. ” Mater. Horiz., 20185(4), 745-752.

[6] Hu, K. #, Yin, F. #, Yu, M., Sun, C., Li, J., Liang, Y., Li, W., Xie, M., Lao, Y., Liang, W. & Li, Z. “In-tether chiral center induced helical peptide modulators target p53-mdm2/mdmx and inhibit tumor growth in stem-like cancer cell. ” Theranostics, 2018, 8(20):5660-5661.




教学工作

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